The Costa Rican node serves as a vital resource for researchers, clinicians, and policymakers, providing up-to-date and comprehensive datasets on pathogens. This node has been established at the Universidad de Costa Rica with the support of the Swiss Institute of Bioinformatics (SIB) to incorporate Costa Rica as a regional node of the Pathogens Portal.

The Hungarian node offers access to a wide range of datasets, services, and tools related to pandemic preparedness. It is designed to serve researchers, clinicians, and policymakers by providing access to an extensive collection of biomolecular data on pathogens. The portal will also serve as the main access point for the Hungarian Pathogen Data Hub, enabling secure, controlled sharing of pathogen data and their associated clinical/epidemiological metadata.

The Mexican node is hosted by the Biotechnology Institute at the National Autonomous University of Mexico (UNAM) and is supported by the Swiss Institute of Bioinformatics (SIB). This initiative builds on the foundation laid by the CoViGen-Mex consortium, which played a central role in genomic surveillance during the COVID-19 pandemic. The Mexican node continues this effort by monitoring pathogens such as SARS-CoV-2, dengue, influenza, RSV, and Mpox, as well as wastewater surveillance. The portal provides up-to-date data, analytical tools, and resources to support the scientific community, health sector, decision-makers, and media in disease surveillance and response.

The Dutch node provides information about available datasets, resources, tools and services related to pathogens research in the Netherlands. It showcases and provides quick access to a collection of biomolecular and other pathogens-related data for Open Science from Dutch institutions and their collaborators.

The Norwegian node provides information about available datasets, resources, tools, and services related to pandemic preparedness in Norway. The portal gives researchers, clinicians and policymakers access to an extensive collection of biomolecular data about pathogens. The portal will also be the main access to the Norwegian Pathogen Data Hub which enables sharing pathogen data and their associated clinical/epidemiological metadata under controlled access.

The Spanish node is a central access point to resources, data, and tools for pathogen surveillance and research in Spain. It features dashboards for national and European initiatives such as EU-WISH (wastewater-based epidemiology), the MePRAM project on precision medicine against antimicrobial resistance, the RELECOV genomic surveillance network for SARS-CoV-2, the National Epidemiological Surveillance Network (RENAVE) and the Acute Respiratory Infection Surveillance System (SiVIRA). The portal also offers bioinformatics pipelines (for bacterial assembly and viral genome reconstruction), training materials on bioinformatics for pathogen genomics, access to datasets and publications, and highlights such as the national priority pathogens list. It covers key public health topics including antimicrobial resistance, genomic surveillance, influenza, RSV, SARS-CoV-2, other viral pathogens, and wastewater surveillance.

The Swedish node was initially launched as part of the COVID-19 National Data Portal Network in June of 2020. It became part of the wider Swedish Pandemic Preparedness effort in 2022, and became a Pathogens Portal node in August 2023. The portal provides direct support for researchers to make infectious disease and pandemic preparedness data more Open and FAIR. It also helps to improve the visibility of openly shared data. The portal contains data on multiple pathogens and from multiple areas of research. This includes, for example, public health data (e.g. vaccination data on COVID-19 and the prevalence of post-COVID-19 condition), wastewater surveillance data from a large number of cities (and multiple viruses, including SARS-CoV-2, enteric viruses, and influenza), and serology data.

The Swiss node was developed to support researchers by providing a one-stop resource for all Swiss pathogen data and projects, fostering collaborations and synergies by creating a forum for discussion, providing documentation and training material on FAIR research data management, especially for pathogen omics data, and showcasing Swiss resources that contribute to pathogen data sharing, access, analysis, and interpretation.